I use an Edge HD 8 SCT and the ASI1600mm camera. I purchased the Artesky Flat Field Generator shown
here. The brightness is USB controlled so you can set a brightness for each filter from your imaging software to get a perfect exposure and the field is perfectly flat. It is a bit pricy but well worth it in my opinion.
Here is my process.
I have previously determined the proper brightness for the flat field Generator (FFG) for each filter. This was done by setting the camera for a 5 second exposure and varying the brightness until the mean value of the image was in the center of the range. This was repeated for each filter and the brightness value for each is recorded in the software (I use SGP).
When taking flats I point the scope straight up and set the FFG right on the top of the scope. A sequence is created for the appropriate number of flats for each filter, each with a 5 second exposure. SGP sends the correct brightness to the panel via USB and then takes the flat frames.
This way I can also take a set of 5 second exposure dark frames and calibrate the flats with flat darks. I do not take bias frames at all.
I get perfect flat frames every time with no problems.
I know Pegasus Astro has a product called the Flatmaster that does the same thing as the Artesky FFG and the size would be more appropriate for your APO, I think.
I hope you find this helpful. If I can answer any questions I am happy to do so.
Best and clear skies!
Tim