I have not personally used that camera, but the specs look like it is 16 bit and your ADU's sound right for calibration. This is a bit puzzling and would lead me to think it could possibly be the algorithm used for calibration or the lights are getting over calibrated so to speak so it gets more added to the final signal than intended. Like the pedestal ADU is lower for lights than the calibration's ADU, but someone else on the forum could comment beyond my experience on that factor. Not sure if flats were taken at the same time as the lights or with the same settings for bit depth.
I didn't see what software you are using to stack, but maybe try DeepSkyStacker as a quick experiment. I haven't seen situaions where that magically fixed an issue I was seeing with PixInsight stacking for example, but some people have seen differences and it is a quick/free experiment to try.
Option 2, and this sounds crazy, but try without the Oiii flats and worst case you should see just the two wide dust donuts but none of the other flat patterns added in. That would conclusively tell you that the flats are contributing instead of correcting vignetting to the final image.
Last idea, I couldn't tell if you had flat darks or biases. In general, if you take darks with the same length as your flats(1.28s as you indicated), it may work better for your particular camera than a bias+ regular darks. That's a frequently debated topic as well and can get into a pretty passionate debate on both sides so I'm just throwing some ideas to try

Good luck on experimenting and hope more people can thow some ideas your way!