I switched a while ago from SharpCap to NINA but realized some funky dark blotchy areas in some of my images. Trying to ascertain what the issue was, I kept checking everything I could think of: camera issues, overall setup (I am in a permanent observatory), my flats, dark flats, and the lights themselves. After sharing some of my subs with a friend (Uwe Deutermann) and chatting with the moderators at APP (since I use APP to calibrate and integrate the subs), the problem was discovered. My dark library was made with SharpCap prior to using NINA. Apparently, that created the issue. So, just as a FYI, if you experience anything like what I did, make sure your darks, and your flats and dark flats for that matter, are done using the same program.