Hi,
Downscaling will work if it is a mono camera but not with an OSC, at least not the ones from ZWO that I know of. The in camera binned image is still undebayered (mono) data formed by superpixels. It is possible to do the same thing in postprocessing but unfortunately not the same thing at all as debayering the unbinned image and downscaling with an RGB outcome. I think it is better to just take new flats. It is not like they change so much from one day to the next.

Cheers,
Dimitris