The circular pattern seen on the “Autosave.jpg” suggests that this is could be a dew or frost issue on the camera glass. This may happen when the camera is cooled to a point far below ambient temperature (say delta T > 30 deg C), and the chance of having these problems grows quickly if the humidity is high. I have seen similar patterns on my IMX 571 sensor as well as on a ZWO 1600 camera in the past.
If you go through the raw image stack, it is sometimes possible to identify that the problem varies across the session, typically starting in the middle of the frame and growing outwards, thus a circular or oval pattern. If the dew / frost has appeared in the first place, it will not go away until the camera is heated for some time again.
It is extremely frustrating, but luckily easy to combat in two simple steps:
Let the camera cool slowly. I let it mine cool down to -15 deg C over a 10 minute period. Previously, I used -20 deg C as standard, but I think it is not worth the extra risk of having dew problems.
Make sure the window heater is turned on in the driver settings. For my camera, it needs to be set to its maximum setting to be effective.
-Martin